Stubborn Quay lock cup door
TNS paid the price for missed chances as they fell at the first hurdle in the Challenge Cup.
Darren Williams' first-leg goal on Deeside proved enough to send Nomads into the next round, after a battling defensive display earned them a goal-less draw at Treflan.
Marc Lloyd-Williams came closest to breaking the deadlock, hitting the crossbar with a 13th minute effort after being put in by Nicky Ward and hitting a post soon after the break from John Toner's right wing cross.
The visitors sounded a wake-up call as early as the first minute, when the ball broke clear to Stuart Rain who was denied by a fine stop from keeper Gerard Doherty.
But Saints were soon on the offensive, with Scott Ruscoe firing wide and Ward shooting over from 12 yards.
Lloyd-Williams went close with a 15-yarder, but the TNS rhythm was disrupted by early injuries to Holmes and Ruscoe, who were both substituted.
In a rare attack sparked by skipper Gareth Owen, Tommy Mutton brought another good save from Doherty just before the break.
Saints created fewer opportunities in the second period and were too often guilty of wayward passing, with little supply to Jiws and Wilde up front.
John Lawless laid on chances for Steven Beck and Lloyd-Williams but as the game wore on it was evident that it was not to be Saints' night and Mutton almost had the last word when he brought another good save from Doherty.